Cyclin-dependent kinase 20 (CDK20)
Homo sapiens — UniProt Q8IZL9
Data last refreshed: (UniProt release unknown)
Key facts
Cyclin-dependent kinase 20 (CDK20) is a protein from Homo sapiens identified by UniProt accession Q8IZL9, 346 residues long. MolForge cross-references it against 0 known binders and 156 disease associations.
- UniProt accession: Q8IZL9; gene symbol CDK20.
- Organism: Homo sapiens.
- Length: 346 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroinflammatory disorder and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclin-dependent kinase 20 |
|---|---|
| UniProt accession | Q8IZL9 |
| Gene | CDK20 |
| Organism | Homo sapiens |
| Length | 346 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (156)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- neuroinflammatory disorder · score 0.34
- attention deficit hyperactivity disorder · score 0.33
- Hearing impairment · score 0.33
- Seizure · score 0.33
- obsessive-compulsive disorder · score 0.33
- Global developmental delay · score 0.26
- Intellectual disability · score 0.26
- body height · score 0.17
- hereditary breast ovarian cancer syndrome · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IZL9-F1 | alphafold | PREDICTED | 85.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IZL9.
Amino-acid sequence (346 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDK20?
The strongest Open Targets associations for CDK20 are neurodegenerative disease, neuroinflammatory disorder, attention deficit hyperactivity disorder, Hearing impairment and Seizure.
How long is the CDK20 protein?
The Homo sapiens CDK20 protein (UniProt Q8IZL9) is 346 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IZL9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IZL9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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