Palmitoyltransferase ZDHHC14 (ZDHHC14)
Homo sapiens — UniProt Q8IZN3
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC14 (ZDHHC14) is a protein from Homo sapiens identified by UniProt accession Q8IZN3, 488 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q8IZN3; gene symbol ZDHHC14.
- Organism: Homo sapiens.
- Length: 488 amino acids.
- Top disease associations (Open Targets): mean platelet volume, Red cell distribution width and gut microbiome measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC14 |
|---|---|
| UniProt accession | Q8IZN3 |
| Gene | ZDHHC14 |
| Organism | Homo sapiens |
| Length | 488 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.50
- Red cell distribution width · score 0.45
- gut microbiome measurement · score 0.32
- platelet component distribution width · score 0.28
- metabolite measurement · score 0.27
- post-traumatic stress disorder · score 0.26
- platelet count · score 0.25
- visual perception measurement · score 0.24
- ulcerative colitis · score 0.19
- PHF-tau measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IZN3-F1 | alphafold | PREDICTED | 72.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IZN3.
Amino-acid sequence (488 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC14?
The strongest Open Targets associations for ZDHHC14 are mean platelet volume, Red cell distribution width, gut microbiome measurement, platelet component distribution width and metabolite measurement.
How long is the ZDHHC14 protein?
The Homo sapiens ZDHHC14 protein (UniProt Q8IZN3) is 488 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IZN3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IZN3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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