Beta-defensin 107 (DEFB107A)
Homo sapiens — UniProt Q8IZN7
Data last refreshed: (UniProt release unknown)
Key facts
Beta-defensin 107 (DEFB107A) is a protein from Homo sapiens identified by UniProt accession Q8IZN7, 70 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8IZN7; gene symbol DEFB107A.
- Organism: Homo sapiens.
- Length: 70 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, emotional symptom measurement and male infertility.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-defensin 107 |
|---|---|
| UniProt accession | Q8IZN7 |
| Gene | DEFB107A |
| Organism | Homo sapiens |
| Length | 70 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.04
- emotional symptom measurement · score 0.02
- male infertility · score 0.01
- renal cell carcinoma · score 0.00
- teratoma · score 0.00
- mastitis · score 0.00
- infect · score 0.00
- infection · score 0.00
- fungal infectious disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IZN7-F1 | alphafold | PREDICTED | 83.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IZN7.
Amino-acid sequence (70 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DEFB107A?
The strongest Open Targets associations for DEFB107A are neuroticism measurement, emotional symptom measurement, male infertility, renal cell carcinoma and teratoma.
How long is the DEFB107A protein?
The Homo sapiens DEFB107A protein (UniProt Q8IZN7) is 70 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IZN7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IZN7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.