Retinol dehydrogenase 10 (RDH10)
Homo sapiens — UniProt Q8IZV5
Data last refreshed: (UniProt release unknown)
Key facts
Retinol dehydrogenase 10 (RDH10) is a protein from Homo sapiens identified by UniProt accession Q8IZV5, 341 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.
- UniProt accession: Q8IZV5; gene symbol RDH10.
- Organism: Homo sapiens.
- Length: 341 amino acids.
- Top disease associations (Open Targets): retinal layer thickness measurement, appendicular lean mass and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Retinol dehydrogenase 10 |
|---|---|
| UniProt accession | Q8IZV5 |
| Gene | RDH10 |
| Organism | Homo sapiens |
| Length | 341 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (102)
Diseases linked to this target (Open Targets).
- retinal layer thickness measurement · score 0.25
- appendicular lean mass · score 0.25
- systolic blood pressure · score 0.22
- retinal nerve fibre layer thickness measurement · score 0.22
- PHF-tau measurement · score 0.20
- Varicose veins · score 0.20
- Abnormality of refraction · score 0.19
- brain measurement · score 0.19
- platelet crit · score 0.18
- platelet count · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8IZV5-F1 | alphafold | PREDICTED | 91.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8IZV5.
Amino-acid sequence (341 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RDH10?
The strongest Open Targets associations for RDH10 are retinal layer thickness measurement, appendicular lean mass, systolic blood pressure, retinal nerve fibre layer thickness measurement and PHF-tau measurement.
How long is the RDH10 protein?
The Homo sapiens RDH10 protein (UniProt Q8IZV5) is 341 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8IZV5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8IZV5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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