Ribosomal biogenesis factor (RBIS)
Homo sapiens — UniProt Q8N0T1
Data last refreshed: (UniProt release unknown)
Key facts
Ribosomal biogenesis factor (RBIS) is a protein from Homo sapiens identified by UniProt accession Q8N0T1, 100 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q8N0T1; gene symbol RBIS.
- Organism: Homo sapiens.
- Length: 100 amino acids.
- Top disease associations (Open Targets): carbonic anhydrase 13 measurement, body mass index and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribosomal biogenesis factor |
|---|---|
| UniProt accession | Q8N0T1 |
| Gene | RBIS |
| Organism | Homo sapiens |
| Length | 100 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- carbonic anhydrase 13 measurement · score 0.03
- body mass index · score 0.03
- PHF-tau measurement · score 0.02
- body weight · score 0.02
- colorectal cancer · score 0.02
- type 1 diabetes mellitus · score 0.00
- acute myeloid leukemia · score 0.00
- hepatocellular carcinoma · score 0.00
- oral squamous cell carcinoma · score 0.00
- disorder of ear · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0T1-F1 | alphafold | PREDICTED | 78.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0T1.
Amino-acid sequence (100 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBIS?
The strongest Open Targets associations for RBIS are carbonic anhydrase 13 measurement, body mass index, PHF-tau measurement, body weight and colorectal cancer.
How long is the RBIS protein?
The Homo sapiens RBIS protein (UniProt Q8N0T1) is 100 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0T1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0T1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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