Protein FAM185A (FAM185A)
Homo sapiens — UniProt Q8N0U4
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM185A (FAM185A) is a protein from Homo sapiens identified by UniProt accession Q8N0U4, 392 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q8N0U4; gene symbol FAM185A.
- Organism: Homo sapiens.
- Length: 392 amino acids.
- Top disease associations (Open Targets): chronotype measurement, type 2 diabetes mellitus and complication.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM185A |
|---|---|
| UniProt accession | Q8N0U4 |
| Gene | FAM185A |
| Organism | Homo sapiens |
| Length | 392 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.31
- type 2 diabetes mellitus · score 0.29
- complication · score 0.20
- circadian rhythm · score 0.17
- diverticular disease · score 0.16
- hemorrhoid · score 0.15
- diverticulitis · score 0.13
- diabetes mellitus · score 0.06
- cortical thickness · score 0.03
- response to cold pressor test · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0U4-F1 | alphafold | PREDICTED | 78.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0U4.
Amino-acid sequence (392 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM185A?
The strongest Open Targets associations for FAM185A are chronotype measurement, type 2 diabetes mellitus, complication, circadian rhythm and diverticular disease.
How long is the FAM185A protein?
The Homo sapiens FAM185A protein (UniProt Q8N0U4) is 392 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0U4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0U4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.