Putative ribosome-binding factor A, mitochondrial (RBFA)
Homo sapiens — UniProt Q8N0V3
Data last refreshed: (UniProt release unknown)
Key facts
Putative ribosome-binding factor A, mitochondrial (RBFA) is a protein from Homo sapiens identified by UniProt accession Q8N0V3, 343 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8N0V3; gene symbol RBFA.
- Organism: Homo sapiens.
- Length: 343 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and aspartate aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative ribosome-binding factor A, mitochondrial |
|---|---|
| UniProt accession | Q8N0V3 |
| Gene | RBFA |
| Organism | Homo sapiens |
| Length | 343 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- lysosomal storage disease · score 0.19
- aspartate aminotransferase measurement · score 0.03
- neutrophil count · score 0.03
- monocyte count · score 0.03
- myeloid white cell count · score 0.03
- leukocyte count · score 0.02
- self reported educational attainment · score 0.02
- infect · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0V3-F1 | alphafold | PREDICTED | 65.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0V3.
Amino-acid sequence (343 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBFA?
The strongest Open Targets associations for RBFA are neurodegenerative disease, lysosomal storage disease, aspartate aminotransferase measurement, neutrophil count and monocyte count.
How long is the RBFA protein?
The Homo sapiens RBFA protein (UniProt Q8N0V3) is 343 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0V3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0V3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.