IQ domain-containing protein K (IQCK)
Homo sapiens — UniProt Q8N0W5
Data last refreshed: (UniProt release unknown)
Key facts
IQ domain-containing protein K (IQCK) is a protein from Homo sapiens identified by UniProt accession Q8N0W5, 287 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q8N0W5; gene symbol IQCK.
- Organism: Homo sapiens.
- Length: 287 amino acids.
- Top disease associations (Open Targets): waist circumference, body mass index and late-onset Alzheimers disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | IQ domain-containing protein K |
|---|---|
| UniProt accession | Q8N0W5 |
| Gene | IQCK |
| Organism | Homo sapiens |
| Length | 287 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- waist circumference · score 0.30
- body mass index · score 0.24
- late-onset Alzheimers disease · score 0.23
- platelet count · score 0.07
- insomnia measurement · score 0.06
- platelet crit · score 0.05
- lean body mass · score 0.04
- obesity · score 0.04
- physical activity measurement · score 0.04
- smoking behavior · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0W5-F1 | alphafold | PREDICTED | 70.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0W5.
Amino-acid sequence (287 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IQCK?
The strongest Open Targets associations for IQCK are waist circumference, body mass index, late-onset Alzheimers disease, platelet count and insomnia measurement.
How long is the IQCK protein?
The Homo sapiens IQCK protein (UniProt Q8N0W5) is 287 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0W5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0W5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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