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FMR1 neighbor protein (FMR1NB)

Homo sapiens — UniProt Q8N0W7

Gene: FMR1NBHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

FMR1 neighbor protein (FMR1NB) is a protein from Homo sapiens identified by UniProt accession Q8N0W7, 255 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

  • UniProt accession: Q8N0W7; gene symbol FMR1NB.
  • Organism: Homo sapiens.
  • Length: 255 amino acids.
  • Top disease associations (Open Targets): monocyte count, type 2 diabetes mellitus and adolescent idiopathic scoliosis.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameFMR1 neighbor protein
UniProt accessionQ8N0W7
GeneFMR1NB
OrganismHomo sapiens
Length255 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • monocyte count · score 0.04
  • type 2 diabetes mellitus · score 0.04
  • adolescent idiopathic scoliosis · score 0.03
  • basophil count · score 0.03
  • fragile X syndrome · score 0.03
  • anti-neutrophil antibody associated vasculitis · score 0.03
  • cancer · score 0.02
  • male homosexuality · score 0.02
  • hepatocellular carcinoma · score 0.01
  • neoplasm · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N0W7-F1alphafoldPREDICTED61.71—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0W7.

Amino-acid sequence (255 residues)

MSSHRRKAKG RNRRSHRAMR VAHLELATYE LAATESNPES SHPGYEAAMA DRPQPGWRES LKMRVSKPFG MLMLSIWILL FVCYYLSYYL CSGSSYFVLA NGHILPNSEN AHGQSLEEDS ALEALLNFFF PTTCNLRENQ VAKPCNELQD LSESECLRHK CCFSSSGTTS FKCFAPFRDV PKQMMQMFGL GAISLILVCL PIYCRSLFWR SEPADDLQRQ DNRVVTGLKK QRRKRKRKSE MLQKAARGRE EHGDE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FMR1NB?

The strongest Open Targets associations for FMR1NB are monocyte count, type 2 diabetes mellitus, adolescent idiopathic scoliosis, basophil count and fragile X syndrome.

How long is the FMR1NB protein?

The Homo sapiens FMR1NB protein (UniProt Q8N0W7) is 255 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N0W7
GeneFMR1NB
OrganismHomo sapiens
Length255
Binders0
Diseases15
View on UniProt