About Sperm-associated antigen 16 protein
Sperm-associated antigen 16 protein (SPAG16) is a protein
from Homo sapiens identified by UniProt accession
Q8N0X2, 631 residues long.
MolForge cross-references it against 0 known binders and
179 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (179)
Diseases linked to this target (Open Targets).
- heart disease · score 0.32
- self reported educational attainment · score 0.26
- attention deficit hyperactivity disorder · score 0.23
- adolescent idiopathic scoliosis · score 0.21
- mathematical ability · score 0.19
- lifestyle measurement · score 0.18
- eosinophil count · score 0.17
- schizophrenia · score 0.17
- Tourette syndrome · score 0.16
- unipolar depression · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q8N0X2.
Amino-acid sequence (631 residues)
MAAQRGMPSS AVRVLEEALG MGLTAAGDAR DTADAVAAEG AYYLEQVTIT EASEDDYEYE EIPDDNFSIP EGEEDLAKAI QMAQEQATDT EILERKTVLP SKHAVPEVIE DFLCNFLIKM GMTRTLDCFQ SEWYELIQKG VTELRTVGNV PDVYTQIMLL ENENKNLKKD LKHYKQAADK AREDLLKIQK ERDFHRMHHK RIVQEKNKLI NDLKGLKLHY ASYEPTIRVL HEKHHTLLKE KMLTSLERDK VVGQISGLQE TLKKLQRGHS YHGPQIKVDH SREKENAPEG PTQKGLREAR EQNKCKTKMK GNTKDSEFPI DMQPNPNLNV SKESLSPAKF DYKLKNIFRL HELPVSCVSM QPHKDILVSC GEDRLWKVLG LPKCNVLLTG FGHTDWLSDC CFHPSGDKLA TSSGDTTVKL WDLCKGDCIL TFEGHSRAVW SCTWHSCGNF VASSSLDKTS KIWDVNSERC RCTLYGHTDS VNSIEFFPFS NTLLTSSADK TLSIWDARTG ICEQSLYGHM HSINDAIFDP RGHMIASCDA CGVTKLWDFR KLLPIVSIDI GPSPGNEVNF DSSGRVLAQA SGNGVIHLLD LKSGEIHKLM GHENEAHTVV FSHDGEILFS GGSDGTVRTW S
Explore Sperm-associated antigen 16 protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets