Zinc finger protein 444 (ZNF444)
Homo sapiens — UniProt Q8N0Y2
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 444 (ZNF444) is a protein from Homo sapiens identified by UniProt accession Q8N0Y2, 327 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q8N0Y2; gene symbol ZNF444.
- Organism: Homo sapiens.
- Length: 327 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, platelet count and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 444 |
|---|---|
| UniProt accession | Q8N0Y2 |
| Gene | ZNF444 |
| Organism | Homo sapiens |
| Length | 327 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- platelet count · score 0.26
- sex hormone-binding globulin measurement · score 0.07
- neoplasm · score 0.01
- malignant myoepithelioma · score 0.01
- invasive breast ductal carcinoma · score 0.00
- Peutz-Jeghers syndrome · score 0.00
- myoepithelial tumor · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0Y2-F1 | alphafold | PREDICTED | 67.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0Y2.
Amino-acid sequence (327 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF444?
The strongest Open Targets associations for ZNF444 are neurodegenerative disease, platelet count, sex hormone-binding globulin measurement, neoplasm and malignant myoepithelioma.
How long is the ZNF444 protein?
The Homo sapiens ZNF444 protein (UniProt Q8N0Y2) is 327 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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