Olfactory receptor 8I2 (OR8I2)
Homo sapiens — UniProt Q8N0Y5
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 8I2 (OR8I2) is a protein from Homo sapiens identified by UniProt accession Q8N0Y5, 310 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8N0Y5; gene symbol OR8I2.
- Organism: Homo sapiens.
- Length: 310 amino acids.
- Top disease associations (Open Targets): thyroid gland adenocarcinoma, clear cell renal carcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 8I2 |
|---|---|
| UniProt accession | Q8N0Y5 |
| Gene | OR8I2 |
| Organism | Homo sapiens |
| Length | 310 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- prostate adenocarcinoma · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- leukocyte count · score 0.02
- gastric carcinoma · score 0.01
- hematocrit · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0Y5-F1 | alphafold | PREDICTED | 89.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0Y5.
Amino-acid sequence (310 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR8I2?
The strongest Open Targets associations for OR8I2 are thyroid gland adenocarcinoma, clear cell renal carcinoma, ovarian cancer, prostate adenocarcinoma and low grade glioma.
How long is the OR8I2 protein?
The Homo sapiens OR8I2 protein (UniProt Q8N0Y5) is 310 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0Y5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0Y5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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