V-set and immunoglobulin domain-containing protein 10 (VSIG10)
Homo sapiens — UniProt Q8N0Z9
Data last refreshed: (UniProt release unknown)
Key facts
V-set and immunoglobulin domain-containing protein 10 (VSIG10) is a protein from Homo sapiens identified by UniProt accession Q8N0Z9, 540 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q8N0Z9; gene symbol VSIG10.
- Organism: Homo sapiens.
- Length: 540 amino acids.
- Top disease associations (Open Targets): blood protein measurement, Red cell distribution width and hemoglobin A1 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | V-set and immunoglobulin domain-containing protein 10 |
|---|---|
| UniProt accession | Q8N0Z9 |
| Gene | VSIG10 |
| Organism | Homo sapiens |
| Length | 540 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.20
- Red cell distribution width · score 0.16
- hemoglobin A1 measurement · score 0.13
- neuroticism measurement · score 0.07
- transient myeloproliferative syndrome · score 0.06
- wellbeing measurement · score 0.05
- neutrophil immunodeficiency syndrome · score 0.05
- depressive symptom measurement · score 0.05
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- monocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N0Z9-F1 | alphafold | PREDICTED | 77.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N0Z9.
Amino-acid sequence (540 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VSIG10?
The strongest Open Targets associations for VSIG10 are blood protein measurement, Red cell distribution width, hemoglobin A1 measurement, neuroticism measurement and transient myeloproliferative syndrome.
How long is the VSIG10 protein?
The Homo sapiens VSIG10 protein (UniProt Q8N0Z9) is 540 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N0Z9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N0Z9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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