UPF0462 protein C4orf33 (C4orf33)
Homo sapiens — UniProt Q8N1A6
Data last refreshed: (UniProt release unknown)
Key facts
UPF0462 protein C4orf33 (C4orf33) is a protein from Homo sapiens identified by UniProt accession Q8N1A6, 199 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q8N1A6; gene symbol C4orf33.
- Organism: Homo sapiens.
- Length: 199 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, urinary metabolite measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0462 protein C4orf33 |
|---|---|
| UniProt accession | Q8N1A6 |
| Gene | C4orf33 |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.42
- urinary metabolite measurement · score 0.31
- mathematical ability · score 0.30
- hip bone mineral density · score 0.24
- hip bone size · score 0.24
- risky sexual behaviour measurement · score 0.22
- fat body mass · score 0.20
- response to trauma exposure · score 0.16
- alcohol use disorder measurement · score 0.16
- lifestyle measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1A6-F1 | alphafold | PREDICTED | 95.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1A6.
Amino-acid sequence (199 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C4orf33?
The strongest Open Targets associations for C4orf33 are serum metabolite measurement, urinary metabolite measurement, mathematical ability, hip bone mineral density and hip bone size.
How long is the C4orf33 protein?
The Homo sapiens C4orf33 protein (UniProt Q8N1A6) is 199 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1A6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1A6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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