Cyclin-Q (CCNQ)
Homo sapiens — UniProt Q8N1B3
Data last refreshed: (UniProt release unknown)
Key facts
Cyclin-Q (CCNQ) is a protein from Homo sapiens identified by UniProt accession Q8N1B3, 248 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q8N1B3; gene symbol CCNQ.
- Organism: Homo sapiens.
- Length: 248 amino acids.
- Top disease associations (Open Targets): syndactyly-telecanthus-anogenital and renal malformations syndrome, Syndactyly - telecanthus - anogenital and renal malformations and hypertriglyceridemia 2.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclin-Q |
|---|---|
| UniProt accession | Q8N1B3 |
| Gene | CCNQ |
| Organism | Homo sapiens |
| Length | 248 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- syndactyly-telecanthus-anogenital and renal malformations syndrome · score 0.67
- Syndactyly - telecanthus - anogenital and renal malformations · score 0.65
- hypertriglyceridemia 2 · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.05
- Fish-eye disease · score 0.05
- hypoalphalipoproteinemia, primary, 1 · score 0.04
- hyperlipidemia due to hepatic triglyceride lipase deficiency · score 0.04
- homozygous familial hypercholesterolemia · score 0.04
- Combined hyperlipidemia · score 0.04
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1B3-F1 | alphafold | PREDICTED | 87.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1B3.
Amino-acid sequence (248 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCNQ?
The strongest Open Targets associations for CCNQ are syndactyly-telecanthus-anogenital and renal malformations syndrome, Syndactyly - telecanthus - anogenital and renal malformations, hypertriglyceridemia 2, cholesterol-ester transfer protein deficiency and Fish-eye disease.
How long is the CCNQ protein?
The Homo sapiens CCNQ protein (UniProt Q8N1B3) is 248 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1B3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1B3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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