Cilia- and flagella-associated protein 107 (CFAP107)
Homo sapiens — UniProt Q8N1D5
Data last refreshed: (UniProt release unknown)
Key facts
Cilia- and flagella-associated protein 107 (CFAP107) is a protein from Homo sapiens identified by UniProt accession Q8N1D5, 194 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q8N1D5; gene symbol CFAP107.
- Organism: Homo sapiens.
- Length: 194 amino acids.
- Top disease associations (Open Targets): central nervous system cancer, Crigler-Najjar syndrome type 2 and transient familial neonatal hyperbilirubinemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cilia- and flagella-associated protein 107 |
|---|---|
| UniProt accession | Q8N1D5 |
| Gene | CFAP107 |
| Organism | Homo sapiens |
| Length | 194 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- central nervous system cancer · score 0.05
- Crigler-Najjar syndrome type 2 · score 0.04
- transient familial neonatal hyperbilirubinemia · score 0.04
- colorectal adenocarcinoma · score 0.04
- psoriasis · score 0.02
- ependymoma · score 0.02
- squamous cell carcinoma · score 0.01
- papillary thyroid carcinoma · score 0.01
- nasopharyngeal neoplasm · score 0.00
- breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1D5-F1 | alphafold | PREDICTED | 79.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1D5.
Amino-acid sequence (194 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CFAP107?
The strongest Open Targets associations for CFAP107 are central nervous system cancer, Crigler-Najjar syndrome type 2, transient familial neonatal hyperbilirubinemia, colorectal adenocarcinoma and psoriasis.
How long is the CFAP107 protein?
The Homo sapiens CFAP107 protein (UniProt Q8N1D5) is 194 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1D5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1D5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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