Lysozyme g-like protein 1 (LYG1)
Homo sapiens — UniProt Q8N1E2
Data last refreshed: (UniProt release unknown)
Key facts
Lysozyme g-like protein 1 (LYG1) is a protein from Homo sapiens identified by UniProt accession Q8N1E2, 194 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q8N1E2; gene symbol LYG1.
- Organism: Homo sapiens.
- Length: 194 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Immature Reticulocyte Fraction Measurement and uterine fibroid.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysozyme g-like protein 1 |
|---|---|
| UniProt accession | Q8N1E2 |
| Gene | LYG1 |
| Organism | Homo sapiens |
| Length | 194 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- Immature Reticulocyte Fraction Measurement · score 0.16
- uterine fibroid · score 0.16
- FEV/FVC ratio · score 0.07
- mathematical ability · score 0.06
- self reported educational attainment · score 0.05
- graft versus host disease · score 0.05
- cognitive function measurement · score 0.04
- reticulocyte count · score 0.04
- combined immunodeficiency with skin granulomas · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1E2-F1 | alphafold | PREDICTED | 82.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1E2.
Amino-acid sequence (194 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LYG1?
The strongest Open Targets associations for LYG1 are neurodegenerative disease, Immature Reticulocyte Fraction Measurement, uterine fibroid, FEV/FVC ratio and mathematical ability.
How long is the LYG1 protein?
The Homo sapiens LYG1 protein (UniProt Q8N1E2) is 194 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1E2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1E2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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