Nuclear pore complex protein Nup93 (NUP93)
Homo sapiens — UniProt Q8N1F7
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear pore complex protein Nup93 (NUP93) is a protein from Homo sapiens identified by UniProt accession Q8N1F7, 819 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.
- UniProt accession: Q8N1F7; gene symbol NUP93.
- Organism: Homo sapiens.
- Length: 819 amino acids.
- Top disease associations (Open Targets): nephrotic syndrome, influenza and HIV infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear pore complex protein Nup93 |
|---|---|
| UniProt accession | Q8N1F7 |
| Gene | NUP93 |
| Organism | Homo sapiens |
| Length | 819 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- nephrotic syndrome · score 0.66
- influenza · score 0.54
- HIV infection · score 0.54
- viral disease · score 0.53
- Alzheimer disease · score 0.46
- Parkinson disease · score 0.46
- neurodegenerative disease · score 0.46
- lysosomal storage disease · score 0.46
- multiple sclerosis · score 0.46
- Histiocytosis · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1F7-F1 | alphafold | PREDICTED | 79.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1F7.
Amino-acid sequence (819 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUP93?
The strongest Open Targets associations for NUP93 are nephrotic syndrome, influenza, HIV infection, viral disease and Alzheimer disease.
How long is the NUP93 protein?
The Homo sapiens NUP93 protein (UniProt Q8N1F7) is 819 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1F7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1F7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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