Serine/threonine-protein kinase 11-interacting protein (STK11IP)
Homo sapiens — UniProt Q8N1F8
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase 11-interacting protein (STK11IP) is a protein from Homo sapiens identified by UniProt accession Q8N1F8, 1088 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q8N1F8; gene symbol STK11IP.
- Organism: Homo sapiens.
- Length: 1088 amino acids.
- Top disease associations (Open Targets): Parkinson disease, Alzheimer disease and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase 11-interacting protein |
|---|---|
| UniProt accession | Q8N1F8 |
| Gene | STK11IP |
| Organism | Homo sapiens |
| Length | 1088 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.25
- Alzheimer disease · score 0.25
- neurodegenerative disease · score 0.25
- multiple sclerosis · score 0.25
- lysosomal storage disease · score 0.25
- body height · score 0.15
- cortical thickness · score 0.15
- genetic disorder · score 0.12
- cardiac hypertrophy · score 0.07
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1F8-F1 | alphafold | PREDICTED | 67.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1F8.
Amino-acid sequence (1088 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STK11IP?
The strongest Open Targets associations for STK11IP are Parkinson disease, Alzheimer disease, neurodegenerative disease, multiple sclerosis and lysosomal storage disease.
How long is the STK11IP protein?
The Homo sapiens STK11IP protein (UniProt Q8N1F8) is 1088 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1F8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1F8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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