Basic leucine zipper transcriptional factor ATF-like 2 (BATF2)
Homo sapiens — UniProt Q8N1L9
Data last refreshed: (UniProt release unknown)
Key facts
Basic leucine zipper transcriptional factor ATF-like 2 (BATF2) is a protein from Homo sapiens identified by UniProt accession Q8N1L9, 274 residues long. MolForge cross-references it against 0 known binders and 108 disease associations.
- UniProt accession: Q8N1L9; gene symbol BATF2.
- Organism: Homo sapiens.
- Length: 274 amino acids.
- Top disease associations (Open Targets): neoplasm, infect and infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Basic leucine zipper transcriptional factor ATF-like 2 |
|---|---|
| UniProt accession | Q8N1L9 |
| Gene | BATF2 |
| Organism | Homo sapiens |
| Length | 274 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (108)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.10
- infect · score 0.09
- infection · score 0.09
- breast cancer · score 0.08
- gonorrhea · score 0.08
- sarcoma · score 0.07
- schistosomiasis · score 0.06
- glioblastoma multiforme · score 0.06
- Barrett's esophagus · score 0.05
- cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1L9-F1 | alphafold | PREDICTED | 61.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1L9.
Amino-acid sequence (274 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BATF2?
The strongest Open Targets associations for BATF2 are neoplasm, infect, infection, breast cancer and gonorrhea.
How long is the BATF2 protein?
The Homo sapiens BATF2 protein (UniProt Q8N1L9) is 274 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1L9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1L9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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