C-type lectin domain family 4 member F (CLEC4F)
Homo sapiens — UniProt Q8N1N0
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 4 member F (CLEC4F) is a protein from Homo sapiens identified by UniProt accession Q8N1N0, 589 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q8N1N0; gene symbol CLEC4F.
- Organism: Homo sapiens.
- Length: 589 amino acids.
- Top disease associations (Open Targets): atopic eczema, seasonal allergic rhinitis and gut microbiome measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 4 member F |
|---|---|
| UniProt accession | Q8N1N0 |
| Gene | CLEC4F |
| Organism | Homo sapiens |
| Length | 589 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- atopic eczema · score 0.13
- seasonal allergic rhinitis · score 0.12
- gut microbiome measurement · score 0.07
- head and neck squamous cell carcinoma · score 0.04
- toxoplasmosis · score 0.03
- Crohn's disease · score 0.03
- chronic kidney disease · score 0.03
- chronic obstructive pulmonary disease · score 0.02
- Systemic lupus erythematosus · score 0.02
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1N0-F1 | alphafold | PREDICTED | 73.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1N0.
Amino-acid sequence (589 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC4F?
The strongest Open Targets associations for CLEC4F are atopic eczema, seasonal allergic rhinitis, gut microbiome measurement, head and neck squamous cell carcinoma and toxoplasmosis.
How long is the CLEC4F protein?
The Homo sapiens CLEC4F protein (UniProt Q8N1N0) is 589 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1N0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1N0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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