Dynactin-associated protein (DYNAP)
Homo sapiens — UniProt Q8N1N2
Data last refreshed: (UniProt release unknown)
Key facts
Dynactin-associated protein (DYNAP) is a protein from Homo sapiens identified by UniProt accession Q8N1N2, 184 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q8N1N2; gene symbol DYNAP.
- Organism: Homo sapiens.
- Length: 184 amino acids.
- Top disease associations (Open Targets): cortical thickness, mood instability measurement and neuroticism measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynactin-associated protein |
|---|---|
| UniProt accession | Q8N1N2 |
| Gene | DYNAP |
| Organism | Homo sapiens |
| Length | 184 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- cortical thickness · score 0.27
- mood instability measurement · score 0.12
- neuroticism measurement · score 0.11
- unipolar depression · score 0.10
- wellbeing measurement · score 0.09
- neurotic disorder · score 0.08
- smoking status measurement · score 0.08
- depressive symptom measurement · score 0.08
- mood disorder · score 0.07
- neoplasm · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1N2-F1 | alphafold | PREDICTED | 59.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1N2.
Amino-acid sequence (184 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DYNAP?
The strongest Open Targets associations for DYNAP are cortical thickness, mood instability measurement, neuroticism measurement, unipolar depression and wellbeing measurement.
How long is the DYNAP protein?
The Homo sapiens DYNAP protein (UniProt Q8N1N2) is 184 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1N2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1N2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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