Zinc transporter ZIP11 (SLC39A11)
Homo sapiens — UniProt Q8N1S5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc transporter ZIP11 (SLC39A11) is a protein from Homo sapiens identified by UniProt accession Q8N1S5, 342 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q8N1S5; gene symbol SLC39A11.
- Organism: Homo sapiens.
- Length: 342 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): ulcerative colitis, type 2 diabetes mellitus and inflammatory bowel disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc transporter ZIP11 |
|---|---|
| UniProt accession | Q8N1S5 |
| Gene | SLC39A11 |
| Organism | Homo sapiens |
| Length | 342 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- ulcerative colitis · score 0.38
- type 2 diabetes mellitus · score 0.35
- inflammatory bowel disease · score 0.33
- lean body mass · score 0.32
- body fat percentage · score 0.31
- gut microbiome measurement · score 0.30
- fat body mass · score 0.28
- body weight · score 0.26
- Crohn's disease · score 0.26
- psoriasis · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N1S5-F1 | alphafold | PREDICTED | 76.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N1S5.
Amino-acid sequence (342 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC39A11?
The strongest Open Targets associations for SLC39A11 are ulcerative colitis, type 2 diabetes mellitus, inflammatory bowel disease, lean body mass and body fat percentage.
How long is the SLC39A11 protein?
The Homo sapiens SLC39A11 protein (UniProt Q8N1S5) is 342 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N1S5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N1S5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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