GH3 domain-containing protein (GHDC)
Homo sapiens — UniProt Q8N2G8
Data last refreshed: (UniProt release unknown)
Key facts
GH3 domain-containing protein (GHDC) is a protein from Homo sapiens identified by UniProt accession Q8N2G8, 530 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q8N2G8; gene symbol GHDC.
- Organism: Homo sapiens.
- Length: 530 amino acids.
- Top disease associations (Open Targets): eosinophil count, pulse pressure measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GH3 domain-containing protein |
|---|---|
| UniProt accession | Q8N2G8 |
| Gene | GHDC |
| Organism | Homo sapiens |
| Length | 530 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.04
- pulse pressure measurement · score 0.02
- mean corpuscular volume · score 0.02
- mean reticulocyte volume · score 0.02
- cystatin C measurement · score 0.02
- acute promyelocytic leukemia · score 0.01
- diabetic nephropathy · score 0.01
- neoplasm · score 0.00
- axial length measurement · score 0.00
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N2G8-F1 | alphafold | PREDICTED | 82.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N2G8.
Amino-acid sequence (530 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GHDC?
The strongest Open Targets associations for GHDC are eosinophil count, pulse pressure measurement, mean corpuscular volume, mean reticulocyte volume and cystatin C measurement.
How long is the GHDC protein?
The Homo sapiens GHDC protein (UniProt Q8N2G8) is 530 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N2G8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N2G8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.