Ankyrin repeat domain-containing protein 36B (ANKRD36B)
Homo sapiens — UniProt Q8N2N9
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 36B (ANKRD36B) is a protein from Homo sapiens identified by UniProt accession Q8N2N9, 1353 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q8N2N9; gene symbol ANKRD36B.
- Organism: Homo sapiens.
- Length: 1353 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, hypothyroidism and Thyroid preparation use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 36B |
|---|---|
| UniProt accession | Q8N2N9 |
| Gene | ANKRD36B |
| Organism | Homo sapiens |
| Length | 1353 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.11
- hypothyroidism · score 0.10
- Thyroid preparation use measurement · score 0.07
- autoimmune disease · score 0.07
- thyroid disease · score 0.05
- eosinophil count · score 0.04
- eosinophil percentage of leukocytes · score 0.04
- mean corpuscular volume · score 0.04
- mean reticulocyte volume · score 0.04
- serum non-albumin protein measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N2N9-F1 | alphafold | PREDICTED | 59.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N2N9.
Amino-acid sequence (1353 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD36B?
The strongest Open Targets associations for ANKRD36B are self reported educational attainment, hypothyroidism, Thyroid preparation use measurement, autoimmune disease and thyroid disease.
How long is the ANKRD36B protein?
The Homo sapiens ANKRD36B protein (UniProt Q8N2N9) is 1353 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N2N9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N2N9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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