Protein odd-skipped-related 2 (OSR2)
Homo sapiens — UniProt Q8N2R0
Data last refreshed: (UniProt release unknown)
Key facts
Protein odd-skipped-related 2 (OSR2) is a protein from Homo sapiens identified by UniProt accession Q8N2R0, 312 residues long. MolForge cross-references it against 0 known binders and 222 disease associations.
- UniProt accession: Q8N2R0; gene symbol OSR2.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): erythrocyte count, gut microbiome measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein odd-skipped-related 2 |
|---|---|
| UniProt accession | Q8N2R0 |
| Gene | OSR2 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (222)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.13
- gut microbiome measurement · score 0.13
- mean corpuscular volume · score 0.10
- chromosome 22q11.2 microduplication syndrome · score 0.10
- Hypomaturation amelogenesis imperfecta · score 0.09
- Hypoplastic amelogenesis imperfecta · score 0.09
- tooth agenesis · score 0.08
- dentin dysplasia type I · score 0.07
- dentin dysplasia type II · score 0.07
- tooth agenesis, selective, 7 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N2R0-F1 | alphafold | PREDICTED | 60.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N2R0.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OSR2?
The strongest Open Targets associations for OSR2 are erythrocyte count, gut microbiome measurement, mean corpuscular volume, chromosome 22q11.2 microduplication syndrome and Hypomaturation amelogenesis imperfecta.
How long is the OSR2 protein?
The Homo sapiens OSR2 protein (UniProt Q8N2R0) is 312 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N2R0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N2R0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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