Solute carrier family 66 member 2 (SLC66A2)
Homo sapiens — UniProt Q8N2U9
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 66 member 2 (SLC66A2) is a protein from Homo sapiens identified by UniProt accession Q8N2U9, 271 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q8N2U9; gene symbol SLC66A2.
- Organism: Homo sapiens.
- Length: 271 amino acids.
- Top disease associations (Open Targets): schizophrenia, appendicular lean mass and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 66 member 2 |
|---|---|
| UniProt accession | Q8N2U9 |
| Gene | SLC66A2 |
| Organism | Homo sapiens |
| Length | 271 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.33
- appendicular lean mass · score 0.21
- self reported educational attainment · score 0.07
- aspartate aminotransferase measurement · score 0.07
- response to isoquinoline alkaloid · score 0.06
- age at first sexual intercourse measurement · score 0.05
- wellbeing measurement · score 0.04
- depressive symptom measurement · score 0.04
- neuroticism measurement · score 0.04
- monocyte count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N2U9-F1 | alphafold | PREDICTED | 85.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N2U9.
Amino-acid sequence (271 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC66A2?
The strongest Open Targets associations for SLC66A2 are schizophrenia, appendicular lean mass, self reported educational attainment, aspartate aminotransferase measurement and response to isoquinoline alkaloid.
How long is the SLC66A2 protein?
The Homo sapiens SLC66A2 protein (UniProt Q8N2U9) is 271 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N2U9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N2U9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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