Centromere protein S (CENPS)
Homo sapiens — UniProt Q8N2Z9
Data last refreshed: (UniProt release unknown)
Key facts
Centromere protein S (CENPS) is a protein from Homo sapiens identified by UniProt accession Q8N2Z9, 138 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q8N2Z9; gene symbol CENPS.
- Organism: Homo sapiens.
- Length: 138 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, urate measurement and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Centromere protein S |
|---|---|
| UniProt accession | Q8N2Z9 |
| Gene | CENPS |
| Organism | Homo sapiens |
| Length | 138 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.24
- urate measurement · score 0.19
- hemoglobin measurement · score 0.12
- hematocrit · score 0.12
- neutrophil count · score 0.10
- whole body water mass · score 0.08
- neoplasm · score 0.05
- neuroblastoma · score 0.05
- forced expiratory volume · score 0.05
- Abnormality of refraction · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N2Z9-F1 | alphafold | PREDICTED | 89.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N2Z9.
Amino-acid sequence (138 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CENPS?
The strongest Open Targets associations for CENPS are C-reactive protein measurement, urate measurement, hemoglobin measurement, hematocrit and neutrophil count.
How long is the CENPS protein?
The Homo sapiens CENPS protein (UniProt Q8N2Z9) is 138 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N2Z9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N2Z9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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