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Olfactory receptor 2L13 (OR2L13)

Homo sapiens — UniProt Q8N349

Gene: OR2L13Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Olfactory receptor 2L13 (OR2L13) is a protein from Homo sapiens identified by UniProt accession Q8N349, 312 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.

  • UniProt accession: Q8N349; gene symbol OR2L13.
  • Organism: Homo sapiens.
  • Length: 312 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, ovarian cancer and chronic lymphocytic leukemia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOlfactory receptor 2L13
UniProt accessionQ8N349
GeneOR2L13
OrganismHomo sapiens
Length312 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (53)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.33
  • ovarian cancer · score 0.18
  • chronic lymphocytic leukemia · score 0.18
  • clear cell renal carcinoma · score 0.18
  • breast adenocarcinoma · score 0.18
  • achalasia-alacrima syndrome · score 0.07
  • thrombocytopenia 7 · score 0.06
  • bleeding disorder, platelet-type, 24 · score 0.05
  • beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.05
  • Glanzmann thrombasthenia 1 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N349-F1alphafoldPREDICTED90.23—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N349.

Amino-acid sequence (312 residues)

MEKWNHTSND FILLGLLPPN QTGIFLLCLI ILIFFLASVG NSAMIHLIHV DPRLHTPMYF LLSQLSLMDL MYISTTVPKM AYNFLSGQKG ISFLGCGVQS FFFLTMACSE GLLLTSMAYD RYLAICHSLY YPIRMSKMMC VKMIGGSWTL GSINSLAHTV FALHIPYCRS RAIDHFFCDV PAMLLLACTD TWVYEYMVFV STSLFLLFPF IGITSSCGRV LFAVYHMHSK EGRKKAFTTI STHLTVVIFY YAPFVYTYLR PRNLRSPAED KILAVFYTIL TPMLNPIIYS LRNKEVLGAM RRVFGIFSFL KE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OR2L13?

The strongest Open Targets associations for OR2L13 are neurodegenerative disease, ovarian cancer, chronic lymphocytic leukemia, clear cell renal carcinoma and breast adenocarcinoma.

How long is the OR2L13 protein?

The Homo sapiens OR2L13 protein (UniProt Q8N349) is 312 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N349
GeneOR2L13
OrganismHomo sapiens
Length312
Binders0
Diseases53
View on UniProt