Chemokine-like protein TAFA-2 (TAFA2)
Homo sapiens — UniProt Q8N3H0
Data last refreshed: (UniProt release unknown)
Key facts
Chemokine-like protein TAFA-2 (TAFA2) is a protein from Homo sapiens identified by UniProt accession Q8N3H0, 131 residues long. MolForge cross-references it against 0 known binders and 97 disease associations.
- UniProt accession: Q8N3H0; gene symbol TAFA2.
- Organism: Homo sapiens.
- Length: 131 amino acids.
- Top disease associations (Open Targets): body mass index, smoking status measurement and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chemokine-like protein TAFA-2 |
|---|---|
| UniProt accession | Q8N3H0 |
| Gene | TAFA2 |
| Organism | Homo sapiens |
| Length | 131 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (97)
Diseases linked to this target (Open Targets).
- body mass index · score 0.39
- smoking status measurement · score 0.38
- diastolic blood pressure · score 0.36
- self reported educational attainment · score 0.35
- platelet component distribution width · score 0.28
- musculoskeletal system disease · score 0.25
- eosinophil count · score 0.24
- platelet crit · score 0.24
- aortic measurement · score 0.22
- platelet count · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3H0-F1 | alphafold | PREDICTED | 88.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3H0.
Amino-acid sequence (131 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAFA2?
The strongest Open Targets associations for TAFA2 are body mass index, smoking status measurement, diastolic blood pressure, self reported educational attainment and platelet component distribution width.
How long is the TAFA2 protein?
The Homo sapiens TAFA2 protein (UniProt Q8N3H0) is 131 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3H0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3H0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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