Cell adhesion molecule 2 (CADM2)
Homo sapiens — UniProt Q8N3J6
Data last refreshed: (UniProt release unknown)
Key facts
Cell adhesion molecule 2 (CADM2) is a protein from Homo sapiens identified by UniProt accession Q8N3J6, 435 residues long. MolForge cross-references it against 0 known binders and 158 disease associations.
- UniProt accession: Q8N3J6; gene symbol CADM2.
- Organism: Homo sapiens.
- Length: 435 amino acids.
- Top disease associations (Open Targets): risk-taking behaviour, body mass index and glaucoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cell adhesion molecule 2 |
|---|---|
| UniProt accession | Q8N3J6 |
| Gene | CADM2 |
| Organism | Homo sapiens |
| Length | 435 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (158)
Diseases linked to this target (Open Targets).
- risk-taking behaviour · score 0.50
- body mass index · score 0.49
- glaucoma · score 0.48
- self reported educational attainment · score 0.46
- mathematical ability · score 0.45
- alcohol consumption measurement · score 0.45
- cognitive function measurement · score 0.44
- diet measurement · score 0.44
- body weight · score 0.44
- systolic blood pressure · score 0.44
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3J6-F1 | alphafold | PREDICTED | 82.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3J6.
Amino-acid sequence (435 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CADM2?
The strongest Open Targets associations for CADM2 are risk-taking behaviour, body mass index, glaucoma, self reported educational attainment and mathematical ability.
How long is the CADM2 protein?
The Homo sapiens CADM2 protein (UniProt Q8N3J6) is 435 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3J6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3J6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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