Zinc finger protein 664 (ZNF664)
Homo sapiens — UniProt Q8N3J9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 664 (ZNF664) is a protein from Homo sapiens identified by UniProt accession Q8N3J9, 261 residues long. MolForge cross-references it against 0 known binders and 88 disease associations.
- UniProt accession: Q8N3J9; gene symbol ZNF664.
- Organism: Homo sapiens.
- Length: 261 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, BMI-adjusted waist-hip ratio and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 664 |
|---|---|
| UniProt accession | Q8N3J9 |
| Gene | ZNF664 |
| Organism | Homo sapiens |
| Length | 261 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (88)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- BMI-adjusted waist-hip ratio · score 0.33
- high density lipoprotein cholesterol measurement · score 0.33
- sex hormone-binding globulin measurement · score 0.29
- triglyceride measurement · score 0.28
- BMI-adjusted waist circumference · score 0.27
- body fat percentage · score 0.27
- fat body mass · score 0.24
- hip circumference · score 0.22
- lean body mass · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3J9-F1 | alphafold | PREDICTED | 91.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3J9.
Amino-acid sequence (261 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF664?
The strongest Open Targets associations for ZNF664 are neurodegenerative disease, BMI-adjusted waist-hip ratio, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement and triglyceride measurement.
How long is the ZNF664 protein?
The Homo sapiens ZNF664 protein (UniProt Q8N3J9) is 261 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3J9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3J9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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