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Beta-taxilin (TXLNB)

Homo sapiens — UniProt Q8N3L3

Gene: TXLNBHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Beta-taxilin (TXLNB) is a protein from Homo sapiens identified by UniProt accession Q8N3L3, 684 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

  • UniProt accession: Q8N3L3; gene symbol TXLNB.
  • Organism: Homo sapiens.
  • Length: 684 amino acids.
  • Top disease associations (Open Targets): heel bone mineral density, total blood protein measurement and serum non-albumin protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameBeta-taxilin
UniProt accessionQ8N3L3
GeneTXLNB
OrganismHomo sapiens
Length684 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (68)

Diseases linked to this target (Open Targets).

  • heel bone mineral density · score 0.43
  • total blood protein measurement · score 0.37
  • serum non-albumin protein measurement · score 0.33
  • albumin:globulin ratio measurement · score 0.26
  • gut microbiome measurement · score 0.17
  • body height · score 0.16
  • Red cell distribution width · score 0.15
  • cortical surface area measurement · score 0.14
  • brain measurement · score 0.11
  • mean corpuscular volume · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N3L3-F1alphafoldPREDICTED67.09—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3L3.

Amino-acid sequence (684 residues)

MEANHSEQLS AERQSTPPGD SSSLPSHNGL EKEDGQDSPT PVQPPEKEAS VHPDISEELN RQLEDIINTY GSAASTAGKE GSARASEQPE NAESPDNEDG DCEETTEEAG REPVASGEPP TVKEPVSNKE QKLEKKILKG LGKEANLLMQ NLNKLQTPEE KFDFLFKKYA ELLDEHRTEQ KKLKLLQKKQ VQIQKEKDQL QGEHSRAILA RSKLESLCRE LQRHNKTLKE EALQRAREEE EKRKEITSHF QSTLTDIQGQ IEQQSERNMK LCQENTELAE KLKSIIDQYE LREEHLDKIF KHRELQQKLV DAKLEQAQEM MKEAEERHKR EKEYLLNQAA EWKLQAKVLK EQETVLQAQL TLYSGRFEEF QSTLTKSNEV FATFKQEMDK TTKKMKKLEK DTATWKARFE NCNKALLDMI EEKALRAKEY ECFVMKIGRL ENLCRALQEE RNELHKKIRD AEISEKDDQS QHNSDEEPES NVSVDQEIDA EEVNSVQTAV KNLATAFMII HHPESTPHQS KETQPEIGSS QESADAALKE PEQPPLIPSR DSESPLPPLT PQAEAEGGSD AEPPSKASNS PAGLGAETQC EGLPVGAQAD QASWKPEAEA SGQAPQAPTE ASLQKMEADV PAPACAAEEH VAAMVPACEP SRQPPRAAAE ELPVGASAGP QPRNVADTNL EGVD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TXLNB?

The strongest Open Targets associations for TXLNB are heel bone mineral density, total blood protein measurement, serum non-albumin protein measurement, albumin:globulin ratio measurement and gut microbiome measurement.

How long is the TXLNB protein?

The Homo sapiens TXLNB protein (UniProt Q8N3L3) is 684 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N3L3
GeneTXLNB
OrganismHomo sapiens
Length684
Binders0
Diseases68
View on UniProt