Protein PHTF2 (PHTF2)
Homo sapiens — UniProt Q8N3S3
Data last refreshed: (UniProt release unknown)
Key facts
Protein PHTF2 (PHTF2) is a protein from Homo sapiens identified by UniProt accession Q8N3S3, 785 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q8N3S3; gene symbol PHTF2.
- Organism: Homo sapiens.
- Length: 785 amino acids.
- Top disease associations (Open Targets): calcium measurement, creatinine measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein PHTF2 |
|---|---|
| UniProt accession | Q8N3S3 |
| Gene | PHTF2 |
| Organism | Homo sapiens |
| Length | 785 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.42
- creatinine measurement · score 0.40
- glomerular filtration rate · score 0.39
- BMI-adjusted waist-hip ratio · score 0.38
- systolic blood pressure · score 0.38
- body height · score 0.35
- neurodegenerative disease · score 0.30
- pulse pressure measurement · score 0.30
- sex hormone-binding globulin measurement · score 0.29
- metabolite measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3S3-F1 | alphafold | PREDICTED | 59.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3S3.
Amino-acid sequence (785 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PHTF2?
The strongest Open Targets associations for PHTF2 are calcium measurement, creatinine measurement, glomerular filtration rate, BMI-adjusted waist-hip ratio and systolic blood pressure.
How long is the PHTF2 protein?
The Homo sapiens PHTF2 protein (UniProt Q8N3S3) is 785 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3S3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3S3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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