Polypeptide N-acetylgalactosaminyltransferase 15 (GALNT15)
Homo sapiens — UniProt Q8N3T1
Data last refreshed: (UniProt release unknown)
Key facts
Polypeptide N-acetylgalactosaminyltransferase 15 (GALNT15) is a protein from Homo sapiens identified by UniProt accession Q8N3T1, 639 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q8N3T1; gene symbol GALNT15.
- Organism: Homo sapiens.
- Length: 639 amino acids.
- Top disease associations (Open Targets): diffuse plaque measurement, protein measurement and refractive error.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 15 |
|---|---|
| UniProt accession | Q8N3T1 |
| Gene | GALNT15 |
| Organism | Homo sapiens |
| Length | 639 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- diffuse plaque measurement · score 0.30
- protein measurement · score 0.29
- refractive error · score 0.06
- age at onset · score 0.05
- Myopia · score 0.05
- Abnormality of refraction · score 0.05
- Crohn's disease · score 0.02
- hepatocellular carcinoma · score 0.02
- esophageal squamous cell carcinoma · score 0.01
- myxosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3T1-F1 | alphafold | PREDICTED | 78.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3T1.
Amino-acid sequence (639 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GALNT15?
The strongest Open Targets associations for GALNT15 are diffuse plaque measurement, protein measurement, refractive error, age at onset and Myopia.
How long is the GALNT15 protein?
The Homo sapiens GALNT15 protein (UniProt Q8N3T1) is 639 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3T1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3T1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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