Transmembrane protein 132C (TMEM132C)
Homo sapiens — UniProt Q8N3T6
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 132C (TMEM132C) is a protein from Homo sapiens identified by UniProt accession Q8N3T6, 1108 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q8N3T6; gene symbol TMEM132C.
- Organism: Homo sapiens.
- Length: 1108 amino acids.
- Top disease associations (Open Targets): blood protein measurement, PHF-tau measurement and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 132C |
|---|---|
| UniProt accession | Q8N3T6 |
| Gene | TMEM132C |
| Organism | Homo sapiens |
| Length | 1108 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.43
- PHF-tau measurement · score 0.38
- neurofibrillary tangles measurement · score 0.32
- electroencephalogram measurement · score 0.31
- empathy measurement · score 0.31
- depressive symptom measurement · score 0.27
- herpes virus seropositivity · score 0.27
- neurodegenerative disease · score 0.22
- sphingomyelin measurement · score 0.20
- depressive episode measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3T6-F1 | alphafold | PREDICTED | 69.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3T6.
Amino-acid sequence (1108 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM132C?
The strongest Open Targets associations for TMEM132C are blood protein measurement, PHF-tau measurement, neurofibrillary tangles measurement, electroencephalogram measurement and empathy measurement.
How long is the TMEM132C protein?
The Homo sapiens TMEM132C protein (UniProt Q8N3T6) is 1108 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3T6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3T6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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