Synaptopodin (SYNPO)
Homo sapiens — UniProt Q8N3V7
Data last refreshed: (UniProt release unknown)
Key facts
Synaptopodin (SYNPO) is a protein from Homo sapiens identified by UniProt accession Q8N3V7, 929 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.
- UniProt accession: Q8N3V7; gene symbol SYNPO.
- Organism: Homo sapiens.
- Length: 929 amino acids.
- Top disease associations (Open Targets): hematocrit, nephrotic syndrome and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptopodin |
|---|---|
| UniProt accession | Q8N3V7 |
| Gene | SYNPO |
| Organism | Homo sapiens |
| Length | 929 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (116)
Diseases linked to this target (Open Targets).
- hematocrit · score 0.31
- nephrotic syndrome · score 0.26
- leukocyte count · score 0.25
- erythrocyte count · score 0.25
- hemoglobin measurement · score 0.24
- red blood cell density measurement · score 0.24
- Non-steroidal anti-inflammatory and antirheumatic product use measurement · score 0.20
- focal segmental glomerulosclerosis · score 0.13
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.12
- PHF-tau measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3V7-F1 | alphafold | PREDICTED | 50.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3V7.
Amino-acid sequence (929 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYNPO?
The strongest Open Targets associations for SYNPO are hematocrit, nephrotic syndrome, leukocyte count, erythrocyte count and hemoglobin measurement.
How long is the SYNPO protein?
The Homo sapiens SYNPO protein (UniProt Q8N3V7) is 929 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3V7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3V7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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