Formin-binding protein 4 (FNBP4)
Homo sapiens — UniProt Q8N3X1
Data last refreshed: (UniProt release unknown)
Key facts
Formin-binding protein 4 (FNBP4) is a protein from Homo sapiens identified by UniProt accession Q8N3X1, 1017 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q8N3X1; gene symbol FNBP4.
- Organism: Homo sapiens.
- Length: 1017 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, eosinophil count and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Formin-binding protein 4 |
|---|---|
| UniProt accession | Q8N3X1 |
| Gene | FNBP4 |
| Organism | Homo sapiens |
| Length | 1017 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- eosinophil count · score 0.21
- systolic blood pressure · score 0.20
- alcohol consumption measurement · score 0.17
- alcohol use disorder measurement · score 0.15
- type 2 diabetes mellitus · score 0.13
- urate measurement · score 0.12
- sex hormone-binding globulin measurement · score 0.11
- myeloid white cell count · score 0.10
- body mass index · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3X1-F1 | alphafold | PREDICTED | 55.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3X1.
Amino-acid sequence (1017 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNBP4?
The strongest Open Targets associations for FNBP4 are neurodegenerative disease, eosinophil count, systolic blood pressure, alcohol consumption measurement and alcohol use disorder measurement.
How long is the FNBP4 protein?
The Homo sapiens FNBP4 protein (UniProt Q8N3X1) is 1017 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3X1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3X1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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