Inactive serine protease 35 (PRSS35)
Homo sapiens — UniProt Q8N3Z0
Data last refreshed: (UniProt release unknown)
Key facts
Inactive serine protease 35 (PRSS35) is a protein from Homo sapiens identified by UniProt accession Q8N3Z0, 413 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q8N3Z0; gene symbol PRSS35.
- Organism: Homo sapiens.
- Length: 413 amino acids.
- Top disease associations (Open Targets): daytime rest measurement, body height and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inactive serine protease 35 |
|---|---|
| UniProt accession | Q8N3Z0 |
| Gene | PRSS35 |
| Organism | Homo sapiens |
| Length | 413 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- daytime rest measurement · score 0.12
- body height · score 0.11
- hepatocellular carcinoma · score 0.08
- retinal layer thickness measurement · score 0.06
- neoplasm · score 0.05
- schizophrenia · score 0.04
- snoring measurement · score 0.04
- cortical thickness · score 0.04
- bipolar disorder · score 0.03
- Testicular regression syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3Z0-F1 | alphafold | PREDICTED | 79.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3Z0.
Amino-acid sequence (413 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRSS35?
The strongest Open Targets associations for PRSS35 are daytime rest measurement, body height, hepatocellular carcinoma, retinal layer thickness measurement and neoplasm.
How long is the PRSS35 protein?
The Homo sapiens PRSS35 protein (UniProt Q8N3Z0) is 413 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3Z0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3Z0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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