Zinc finger CCHC domain-containing protein 7 (ZCCHC7)
Homo sapiens — UniProt Q8N3Z6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger CCHC domain-containing protein 7 (ZCCHC7) is a protein from Homo sapiens identified by UniProt accession Q8N3Z6, 543 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q8N3Z6; gene symbol ZCCHC7.
- Organism: Homo sapiens.
- Length: 543 amino acids.
- Top disease associations (Open Targets): body mass index, diastolic blood pressure and chronotype measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger CCHC domain-containing protein 7 |
|---|---|
| UniProt accession | Q8N3Z6 |
| Gene | ZCCHC7 |
| Organism | Homo sapiens |
| Length | 543 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- body mass index · score 0.33
- diastolic blood pressure · score 0.32
- chronotype measurement · score 0.31
- lean body mass · score 0.27
- sleep duration · score 0.25
- unipolar depression · score 0.25
- bipolar disorder · score 0.23
- attention deficit hyperactivity disorder · score 0.22
- waist circumference · score 0.21
- body fat percentage · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N3Z6-F1 | alphafold | PREDICTED | 53.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N3Z6.
Amino-acid sequence (543 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZCCHC7?
The strongest Open Targets associations for ZCCHC7 are body mass index, diastolic blood pressure, chronotype measurement, lean body mass and sleep duration.
How long is the ZCCHC7 protein?
The Homo sapiens ZCCHC7 protein (UniProt Q8N3Z6) is 543 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N3Z6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N3Z6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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