Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4)
Homo sapiens — UniProt Q8N4A0
Data last refreshed: (UniProt release unknown)
Key facts
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) is a protein from Homo sapiens identified by UniProt accession Q8N4A0, 578 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q8N4A0; gene symbol GALNT4.
- Organism: Homo sapiens.
- Length: 578 amino acids.
- Top disease associations (Open Targets): serum gamma-glutamyl transferase measurement, monocyte count and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 4 |
|---|---|
| UniProt accession | Q8N4A0 |
| Gene | GALNT4 |
| Organism | Homo sapiens |
| Length | 578 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.35
- monocyte count · score 0.32
- neurodegenerative disease · score 0.30
- blood protein measurement · score 0.27
- Rare pervasive developmental disorder · score 0.27
- eosinophil count · score 0.26
- monocyte percentage of leukocytes · score 0.25
- IGF-1 measurement · score 0.25
- lymphocyte count · score 0.23
- CMRF35-like molecule 6 measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4A0-F1 | alphafold | PREDICTED | 91.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4A0.
Amino-acid sequence (578 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GALNT4?
The strongest Open Targets associations for GALNT4 are serum gamma-glutamyl transferase measurement, monocyte count, neurodegenerative disease, blood protein measurement and Rare pervasive developmental disorder.
How long is the GALNT4 protein?
The Homo sapiens GALNT4 protein (UniProt Q8N4A0) is 578 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4A0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4A0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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