Sesquipedalian-1 (PHETA1)
Homo sapiens — UniProt Q8N4B1
Data last refreshed: (UniProt release unknown)
Key facts
Sesquipedalian-1 (PHETA1) is a protein from Homo sapiens identified by UniProt accession Q8N4B1, 249 residues long. MolForge cross-references it against 0 known binders and 97 disease associations.
- UniProt accession: Q8N4B1; gene symbol PHETA1.
- Organism: Homo sapiens.
- Length: 249 amino acids.
- Top disease associations (Open Targets): testosterone measurement, mitochondrial DNA measurement and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sesquipedalian-1 |
|---|---|
| UniProt accession | Q8N4B1 |
| Gene | PHETA1 |
| Organism | Homo sapiens |
| Length | 249 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (97)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.33
- mitochondrial DNA measurement · score 0.29
- sex hormone-binding globulin measurement · score 0.22
- aspartate aminotransferase measurement · score 0.17
- systolic blood pressure · score 0.17
- diastolic blood pressure · score 0.14
- smoking status measurement · score 0.14
- gastric carcinoma · score 0.13
- alcohol consumption measurement · score 0.13
- platelet count · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4B1-F1 | alphafold | PREDICTED | 75.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4B1.
Amino-acid sequence (249 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PHETA1?
The strongest Open Targets associations for PHETA1 are testosterone measurement, mitochondrial DNA measurement, sex hormone-binding globulin measurement, aspartate aminotransferase measurement and systolic blood pressure.
How long is the PHETA1 protein?
The Homo sapiens PHETA1 protein (UniProt Q8N4B1) is 249 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4B1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4B1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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