F-box only protein 39 (FBXO39)
Homo sapiens — UniProt Q8N4B4
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 39 (FBXO39) is a protein from Homo sapiens identified by UniProt accession Q8N4B4, 442 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q8N4B4; gene symbol FBXO39.
- Organism: Homo sapiens.
- Length: 442 amino acids.
- Top disease associations (Open Targets): blood metabolite measurement, diffuse plaque measurement and influenza A (H1N1).
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 39 |
|---|---|
| UniProt accession | Q8N4B4 |
| Gene | FBXO39 |
| Organism | Homo sapiens |
| Length | 442 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- blood metabolite measurement · score 0.26
- diffuse plaque measurement · score 0.14
- influenza A (H1N1) · score 0.08
- neutrophil count · score 0.06
- breast cancer · score 0.05
- cervical squamous cell carcinoma · score 0.03
- neoplasm · score 0.02
- systemic lupus erythematosus · score 0.02
- cancer · score 0.02
- nonpapillary renal cell carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4B4-F1 | alphafold | PREDICTED | 92.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4B4.
Amino-acid sequence (442 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO39?
The strongest Open Targets associations for FBXO39 are blood metabolite measurement, diffuse plaque measurement, influenza A (H1N1), neutrophil count and breast cancer.
How long is the FBXO39 protein?
The Homo sapiens FBXO39 protein (UniProt Q8N4B4) is 442 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4B4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4B4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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