Proline-rich protein 18 (PRR18)
Homo sapiens — UniProt Q8N4B5
Data last refreshed: (UniProt release unknown)
Key facts
Proline-rich protein 18 (PRR18) is a protein from Homo sapiens identified by UniProt accession Q8N4B5, 295 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q8N4B5; gene symbol PRR18.
- Organism: Homo sapiens.
- Length: 295 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mastiha supplement exposure measurement and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline-rich protein 18 |
|---|---|
| UniProt accession | Q8N4B5 |
| Gene | PRR18 |
| Organism | Homo sapiens |
| Length | 295 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- mastiha supplement exposure measurement · score 0.24
- hemoglobin measurement · score 0.24
- protein measurement · score 0.21
- mean platelet volume · score 0.18
- red blood cell density measurement · score 0.04
- medulloblastoma · score 0.02
- ventral hernia · score 0.02
- uric acid measurement · score 0.02
- creatinine measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4B5-F1 | alphafold | PREDICTED | 62.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4B5.
Amino-acid sequence (295 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRR18?
The strongest Open Targets associations for PRR18 are neurodegenerative disease, mastiha supplement exposure measurement, hemoglobin measurement, protein measurement and mean platelet volume.
How long is the PRR18 protein?
The Homo sapiens PRR18 protein (UniProt Q8N4B5) is 295 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4B5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4B5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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