Uncharacterized protein C17orf78 (C17orf78)
Homo sapiens — UniProt Q8N4C9
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C17orf78 (C17orf78) is a protein from Homo sapiens identified by UniProt accession Q8N4C9, 275 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8N4C9; gene symbol C17orf78.
- Organism: Homo sapiens.
- Length: 275 amino acids.
- Top disease associations (Open Targets): daytime rest measurement, Crohn's disease and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C17orf78 |
|---|---|
| UniProt accession | Q8N4C9 |
| Gene | C17orf78 |
| Organism | Homo sapiens |
| Length | 275 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- daytime rest measurement · score 0.09
- Crohn's disease · score 0.06
- body mass index · score 0.04
- age at menopause · score 0.03
- hematocrit · score 0.03
- lymphocyte count · score 0.02
- breast carcinoma · score 0.01
- small cell lung carcinoma · score 0.01
- colorectal cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4C9-F1 | alphafold | PREDICTED | 45.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4C9.
Amino-acid sequence (275 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C17orf78?
The strongest Open Targets associations for C17orf78 are daytime rest measurement, Crohn's disease, body mass index, age at menopause and hematocrit.
How long is the C17orf78 protein?
The Homo sapiens C17orf78 protein (UniProt Q8N4C9) is 275 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4C9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4C9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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