Ferritin, mitochondrial (FTMT)
Homo sapiens — UniProt Q8N4E7
Data last refreshed: (UniProt release unknown)
Key facts
Ferritin, mitochondrial (FTMT) is a protein from Homo sapiens identified by UniProt accession Q8N4E7, 242 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q8N4E7; gene symbol FTMT.
- Organism: Homo sapiens.
- Length: 242 amino acids.
- Top disease associations (Open Targets): beta-amyloid 1-42 measurement, left inferior lateral ventricle volume measurement and cerebrospinal fluid biomarker measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ferritin, mitochondrial |
|---|---|
| UniProt accession | Q8N4E7 |
| Gene | FTMT |
| Organism | Homo sapiens |
| Length | 242 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- beta-amyloid 1-42 measurement · score 0.25
- left inferior lateral ventricle volume measurement · score 0.25
- cerebrospinal fluid biomarker measurement · score 0.25
- systolic blood pressure · score 0.24
- Young adult-onset Parkinsonism · score 0.19
- Anti-Toxoplasma gondii IgG measurement · score 0.14
- FEV/FVC ratio · score 0.08
- neoplasm · score 0.05
- cognitive decline measurement · score 0.03
- age-related macular degeneration · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4E7-F1 | alphafold | PREDICTED | 83.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4E7.
Amino-acid sequence (242 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FTMT?
The strongest Open Targets associations for FTMT are beta-amyloid 1-42 measurement, left inferior lateral ventricle volume measurement, cerebrospinal fluid biomarker measurement, systolic blood pressure and Young adult-onset Parkinsonism.
How long is the FTMT protein?
The Homo sapiens FTMT protein (UniProt Q8N4E7) is 242 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4E7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4E7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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