Choline transporter-like protein 3 (SLC44A3)
Homo sapiens — UniProt Q8N4M1
Data last refreshed: (UniProt release unknown)
Key facts
Choline transporter-like protein 3 (SLC44A3) is a protein from Homo sapiens identified by UniProt accession Q8N4M1, 653 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.
- UniProt accession: Q8N4M1; gene symbol SLC44A3.
- Organism: Homo sapiens.
- Length: 653 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): tissue factor measurement, myocardial infarction and hemorrhoid.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Choline transporter-like protein 3 |
|---|---|
| UniProt accession | Q8N4M1 |
| Gene | SLC44A3 |
| Organism | Homo sapiens |
| Length | 653 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (105)
Diseases linked to this target (Open Targets).
- tissue factor measurement · score 0.37
- myocardial infarction · score 0.27
- hemorrhoid · score 0.26
- neutrophil count · score 0.20
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.18
- cutaneous melanoma · score 0.14
- prothrombin time measurement · score 0.12
- retinitis pigmentosa · score 0.07
- Familial exudative vitreoretinopathy · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4M1-F1 | alphafold | PREDICTED | 81.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4M1.
Amino-acid sequence (653 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC44A3?
The strongest Open Targets associations for SLC44A3 are tissue factor measurement, myocardial infarction, hemorrhoid, neutrophil count and glioblastoma multiforme.
How long is the SLC44A3 protein?
The Homo sapiens SLC44A3 protein (UniProt Q8N4M1) is 653 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4M1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4M1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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