Kelch-like protein 36 (KLHL36)
Homo sapiens — UniProt Q8N4N3
Data last refreshed: (UniProt release unknown)
Key facts
Kelch-like protein 36 (KLHL36) is a protein from Homo sapiens identified by UniProt accession Q8N4N3, 616 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8N4N3; gene symbol KLHL36.
- Organism: Homo sapiens.
- Length: 616 amino acids.
- Top disease associations (Open Targets): lymphocyte count, leukocyte count and pancreatic adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kelch-like protein 36 |
|---|---|
| UniProt accession | Q8N4N3 |
| Gene | KLHL36 |
| Organism | Homo sapiens |
| Length | 616 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.03
- leukocyte count · score 0.02
- pancreatic adenocarcinoma · score 0.02
- Fragile skin · score 0.00
- gastric carcinoma · score 0.00
- nervous system disease · score 0.00
- pulmonary tuberculosis · score 0.00
- carcinoma · score 0.00
- glaucoma · score 0.00
- meningococcal infection · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4N3-F1 | alphafold | PREDICTED | 91.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4N3.
Amino-acid sequence (616 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLHL36?
The strongest Open Targets associations for KLHL36 are lymphocyte count, leukocyte count, pancreatic adenocarcinoma, Fragile skin and gastric carcinoma.
How long is the KLHL36 protein?
The Homo sapiens KLHL36 protein (UniProt Q8N4N3) is 616 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4N3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4N3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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