Kinesin-like protein KIF2B (KIF2B)
Homo sapiens — UniProt Q8N4N8
Data last refreshed: (UniProt release unknown)
Key facts
Kinesin-like protein KIF2B (KIF2B) is a protein from Homo sapiens identified by UniProt accession Q8N4N8, 673 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8N4N8; gene symbol KIF2B.
- Organism: Homo sapiens.
- Length: 673 amino acids.
- Top disease associations (Open Targets): smoking status measurement, self reported educational attainment and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kinesin-like protein KIF2B |
|---|---|
| UniProt accession | Q8N4N8 |
| Gene | KIF2B |
| Organism | Homo sapiens |
| Length | 673 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- smoking status measurement · score 0.38
- self reported educational attainment · score 0.31
- body height · score 0.29
- substance abuse · score 0.28
- attention deficit hyperactivity disorder · score 0.28
- antisocial behaviour measurement · score 0.28
- autosomal dominant compelling helio-ophthalmic outburst syndrome · score 0.24
- protein measurement · score 0.23
- PHF-tau measurement · score 0.20
- ovarian cancer · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4N8-F1 | alphafold | PREDICTED | 72.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4N8.
Amino-acid sequence (673 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KIF2B?
The strongest Open Targets associations for KIF2B are smoking status measurement, self reported educational attainment, body height, substance abuse and attention deficit hyperactivity disorder.
How long is the KIF2B protein?
The Homo sapiens KIF2B protein (UniProt Q8N4N8) is 673 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4N8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4N8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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