Leucine-rich repeat-containing protein 71 (LRRC71)
Homo sapiens — UniProt Q8N4P6
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 71 (LRRC71) is a protein from Homo sapiens identified by UniProt accession Q8N4P6, 559 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q8N4P6; gene symbol LRRC71.
- Organism: Homo sapiens.
- Length: 559 amino acids.
- Top disease associations (Open Targets): platelet count, heel bone mineral density and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 71 |
|---|---|
| UniProt accession | Q8N4P6 |
| Gene | LRRC71 |
| Organism | Homo sapiens |
| Length | 559 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- platelet count · score 0.23
- heel bone mineral density · score 0.23
- platelet component distribution width · score 0.22
- appendicular lean mass · score 0.22
- blood protein measurement · score 0.15
- lymphocyte count · score 0.15
- brain measurement · score 0.15
- diet measurement · score 0.14
- serum gamma-glutamyl transferase measurement · score 0.11
- monocyte percentage of leukocytes · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4P6-F1 | alphafold | PREDICTED | 71.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4P6.
Amino-acid sequence (559 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC71?
The strongest Open Targets associations for LRRC71 are platelet count, heel bone mineral density, platelet component distribution width, appendicular lean mass and blood protein measurement.
How long is the LRRC71 protein?
The Homo sapiens LRRC71 protein (UniProt Q8N4P6) is 559 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4P6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4P6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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